5G-TSN系统下的高精度时间同步

第五代移动通信系统(the fifth generation communication system, 5G)与时间敏感网络(time sensitive networking, TSN)集成的5G-TSN系统需要实现高精度的时间同步。为此，提出一种多波束联合的定时同步算法提高同步信号检测成功率，实现高精度5G-TSN时间同步。首先，根据多个波束间的时域关系计算波束间同步信号块的互相关的组合，求出期望作为门限值；然后，利用超过门限值的若干波束进行互相关叠加峰值计算最大峰值对应的时域索引，并完成主同步信号定时同步；最后，利用时频域结合地方式对传播时延进行估计以减少同步误差。仿真结果表明，采用基于多波束联合的定时同步算法，相比传统算法，相关峰值更加显著，能有效地提高定时同步成功率。     

对新时期现代企业安全保卫工作的思考

文章结合科学发展现,就如何做好新时期、新形势下的企业安全保卫工作问题,作了探索与思考.     

Simultaneous mineralization of CO2 and recovery of soluble potassium using earth-abundant potassium feldspar

CO2 capture and storage(CCS) is an important strategy in combatting anthropogenic climate change.However,commercial application of the CCS technique is currently hampered by its high energy expenditure and costs.To overcome this issue,CO2 capture and utilization(CCU) is a promising CO2 disposal method.We,for the first time,developed a promising method to mineralize CO2 using earth-abundant potassium feldspar in order to effectively reduce CO2 emissions.Our experiments demonstrate that,after adding calcium chloride hexahydrate as an additive,the K-feldspar can be transformed to Ca-silicates at 800 C,which can easily mineralize CO2 to form stable calcium carbonate and recover soluble potassium.The conversion of this process reached 84.7%.With further study,the pretreatment temperature can be reduced to 250 C using hydrothermal method by adding the solution of triethanolamine(TEA).The highest conversion can be reached 40.1%.The process of simultaneous mineralization of CO2 and recovery of soluble potassium can be easily implemented in practice and may provide an economically feasible way to tackle global anthropogenic climate change.     

聚硫聚氨酯的合成及其热力学性能

以聚硫橡胶(PS)、聚四氢呋喃(PTMG)、二苯基甲烷二异氰酸酯(DPMDI)为原料,制备聚硫聚氨酯(PS/PU)复合材料。研究了G4、G112、G21C不同型号聚硫橡胶及其质量分数对聚硫聚氨酯复合材料结构和热力学性能的影响,进行了红外分析、差示扫描热分析(DSC),通过TGA确立了热降解活化能。结果表明:G4和G21C型聚硫橡胶改性的聚氨酯具有更好的热稳定性能,其降解活化能可达171.36kJ/mol。     

枯草芽孢杆菌微生态制剂在禽畜养殖中的作用

枯草芽孢杆菌作为一种绿色健康的微生态制剂,具有调节动物肠道平衡、促进营养吸收、提高免疫能力等功能。微生态制剂是抗生素的理想替代品之一,因其可有效防治动物疾病,并且无毒副作用,无残留污染,不产生抗药性,还能促进动物生长发育而在禽畜养殖中广泛应用。通过综述枯草芽孢杆菌的特性、作用机理以及枯草芽孢杆菌微生态制剂在禽畜养殖中的效果,分析了目前微生态制剂存在的问题及解决措施,并展望了其未来发展方向,为后续禽畜养殖提供借鉴和参考。     

PTC124 targets genetic disorders caused by nonsense mutations

Nonsense mutations promote premature translational termination and cause anywhere from 5-70% of the individual cases of most inherited diseases. Studies on nonsense-mediated cystic fibrosis have indicated that boosting specific protein synthesis from <1% to as little as 5% of normal levels may greatly reduce the severity or eliminate the principal manifestations of disease. To address the need for a drug capable of suppressing premature termination, we identified PTC124-a new chemical entity that selectively induces ribosomal readthrough of premature but not normal termination codons. PTC124 activity, optimized using nonsense-containing reporters, promoted dystrophin production in primary muscle cells from humans and mdx mice expressing dystrophin nonsense alleles, and rescued striated muscle function in mdx mice within 2-8 weeks of drug exposure. PTC124 was well tolerated in animals at plasma exposures substantially in excess of those required for nonsense suppression. The selectivity of PTC124 for premature termination codons, its well characterized activity profile, oral bioavailability and pharmacological properties indicate that this drug may have broad clinical potential for the treatment of a large group of genetic disorders with limited or no therapeutic options.     

Genome-wide detection and characterization of positive selection in human populations

With the advent of dense maps of human genetic variation, it is now possible to detect positive natural selection across the human genome. Here we report an analysis of over 3 million polymorphisms from the International HapMap Project Phase 2 (HapMap2). We used 'long-range haplotype' methods, which were developed to identify alleles segregating in a population that have undergone recent selection, and we also developed new methods that are based on cross-population comparisons to discover alleles that have swept to near-fixation within a population. The analysis reveals more than 300 strong candidate regions. Focusing on the strongest 22 regions, we develop a heuristic for scrutinizing these regions to identify candidate targets of selection. In a complementary analysis, we identify 26 non-synonymous, coding, single nucleotide polymorphisms showing regional evidence of positive selection. Examination of these candidates highlights three cases in which two genes in a common biological process have apparently undergone positive selection in the same population:LARGE and DMD, both related to infection by the Lassa virus, in West Africa;SLC24A5 and SLC45A2, both involved in skin pigmentation, in Europe; and EDAR and EDA2R, both involved in development of hair follicles, in Asia.     

红色激光器在节子厚板材合理截断中的应用

在对厚板材加工中存在的合理截断问题进行分析的基础上,以提高主产出材率为目的,提出了解决其现场操作的方法——采用红色激光器确定截断位置,并利用生产实际进行加工实验加以论证.实验表明:红色激光器对节子厚板材在截断时的主产出材率的提高效果十分显著.     

内蒙古地区4种林分类型UVB屏蔽效应研究

选取内蒙古大兴安岭地区和呼和浩特市兴安落叶松、油松、樟子松和白杆4种典型针叶林,利用PC-2型太阳辐射记录仪进行UVB辐射日进程测定,以获得4种典型性针叶林的UVB屏蔽效应;对4种林分UVB屏蔽效率与枝下高、郁闭度等冠层特征因子进行相关分析.结果表明,(1)4种林分对UVB辐射均产生显著消减作用,其屏蔽效应分别为:落叶松(91.2%)、白杆(90.2%)、油松(88.9%)、樟子松(88.2%);但林分类型和时间段的不同对UVB的屏蔽效应均无显著影响.(2)UVB屏蔽效应与林分郁闭度呈正相关关系,相关系数0.635,与冠层呈负相关关系,相关系数0.966,而与林分平均树高,平均枝下高相关性不显著.     

藤黄酸的提取工艺改进

对中药藤黄中的藤黄酸的提取分离进行了方法改进.通过渗漉、吡啶成盐、三次重结晶、置换萃取等步骤得到橙黄色藤黄酸单体.藤黄酸得率为23.9%.并通过IR、MS、1HNMR、13CNMR对藤黄酸进行了结构鉴定.